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Interesting RNA's


tRNA-Phe (1ehz)

First high resolution X-Ray structure, fully elucidated by Kim and Klug independently in 1974.

Structure Resolution = 1.93
Number of Nucleotides = 76
Total Number of Base-pairs = 30
W-C Base-pairs = 20
Non-canonical Base-pairs = 10
Number of Helices = 3

Electrostatic potential map and block representation
Electrostatic potential map calculated using APBS (Baker Group), combined with 3DNA block representation in raster3D format, displayed in pymol.


Secondary Structure of tRNA.
Secondary Structure using s2s, and rnaview for leontis-westhof annotation.



tRNA-Ile (1qu3)

Isoleucine tRNA synthetase with tRNA-Ile and Mupirocin, 1999, Steitz group.

Structure Resolution = 2.90
Number of Nucleotides = 75
Total Number of Base-pairs = 29
W-C Base-pairs = 20
Non-canonical Base-pairs = 9
Number of Helices = 3



DNA-RNA four way junction (1egk)



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P4-P6 Self Splicing Intron (1gid) and intron splicing intermediate Azoarcus sp. pre-tRNA-Ile group I intron (1zzn)



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Contact Map for P4-P6
Image of Contact map.


Hammerhead Ribozyme (1hmh)



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Large Ribosomal Subunit of Haloarcula marismortui (1jj2)


Number of Atoms = 61617
Number of Nucleotides = 2876
Total Number of Base-pairs = 1153
W-C Base-pairs = 735
Non-canonical Base-pairs = 418
Number of Helices = Depends

Ribosome

70S Prokaryotic 4.32 x 10^-18 g or 2600 KDa
RNA:Protein 2:1
Around 21 aa per second are translated